Afterload plays a crucial role in cardiovascular physiology, influencing how the heart functions under varying conditions. The pressure-volume (PV) loops provide a visual representation of cardiac dynamics, where afterload is a key determinant shaping the loop’s position and size. Understanding this relationship is vital for healthcare professionals, students, and researchers in the medical field. What … Read more
Introduction The heart is a complex, efficient pump that performs the vital task of circulating blood throughout the body. Its performance can be assessed using Pressure-Volume (PV) loops, which graphically represent the changes in pressure and volume within the left ventricle during a cardiac cycle. These loops provide a wealth of information about cardiac function, … Read more
The Fontan circulation represents a pivotal approach for managing single-ventricle physiology in congenital heart disease patients. However, the unique physiology of the Fontan system—characterized by the absence of a sub-pulmonary ventricle—has profound implications for cardiovascular dynamics. Pressure-volume (PV) loops provide a robust framework to analyze these hemodynamic alterations, offering insights into how preload, afterload, and … Read more
Understanding the diastolic function of the right ventricle (RV) is crucial in diagnosing and managing various cardiovascular diseases. This article delves into the relaxation and compliance properties of the RV, with an emphasis on the depiction of these properties in Right Ventricle PV Loop filling phases. By understanding the nuances of pressure-volume (PV) loops, clinicians … Read more
CD Leycom is thrilled to unveil BiV Conduct NT™, the latest evolution of our PVLoop software! As the next generation of Conduct NT, this update introduces powerful new features designed to elevate your experience. Check out the video below for a quick glimpse of what’s new!
Aortic stenosis is a severe cardiovascular condition that alters the heart’s function by obstructing blood flow from the left ventricle into the aorta. Understanding how this condition reshapes the dynamics of the pressure-volume loop in aortic stenosis provides essential insights into its pathophysiology. This article delves into the hemodynamic changes caused by aortic stenosis, focusing … Read more
Understanding the dynamics of cardiac function is pivotal for deciphering cardiovascular health and disease. One of the most insightful tools in this realm is the pressure-volume loop, a graphical representation of the relationship between pressure and volume in the cardiac cycle. By capturing the interplay of systolic and diastolic functions, these loops allow clinicians and … Read more
Heart failure is a complex and often progressive condition that can require advanced mechanical assistance when medication and lifestyle changes no longer suffice. One such advanced intervention is the use of a Left Ventricular Assist Device (LVAD), a mechanical pump that aids heart function and blood flow in individuals with severe heart failure. Traditional LVADs … Read more
The assessment of PV loops in transplanted hearts offers critical insights into the functionality and adaptability of the left and right ventricles under the unique physiological conditions of a transplanted heart. This article explores how pressure-volume (PV) loop analysis aids in understanding the performance differences between the left and right ventricles in heart transplant recipients. … Read more
Evaluating the cardiovascular safety of new drugs is a critical component of pharmacology. One of the most reliable tools for this purpose is Pressure-Volume (PV) loop analysis, which provides a real-time assessment of cardiac function by monitoring the relationship between left ventricular pressure and volume. PV loops for safety pharmacology studies have become increasingly important … Read more