CD Leycom provides PV Loop medical devices for real-time cardiac function and performance monitoring

In addition to volume, intra-cardiac pressure is recorded simultaneously to produce continuous real-time images, known as a Pressure-Volume Loop (PV loop) — widely recognized as a “gold standard” of cardiac function and performance.

PV loops provide insights on all aspects of heart function, which has proven to be invaluable for cardiac research, clinical diagnoses, and improving the intra-operative experience for select cardiac interventions where comprehensive quantitative data is needed.

Pressure-Volume (PV) Loop diagram

Pressure-Volume Loops (PV Loops)
for Clinical Diagnoses and Life Science Research

Inca PV Loop System
Inca® PV Loop System

Improve diagnosis, optimize therapy outcomes, and reduce complications in areas related to CRT, Congenital Heart Disease, and more.

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BiV Sigma-M
Bi-Ventricular Sigma-M© PV Loop System

Technology optimized for pressure-volume loop monitoring in both the left and right ventricle simultaneously, providing unique insights on left and right heart interdependence.

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Pressure-Volume (PV) Loop Catheters
PV loop Catheters

CD Leycom’s pressure-volume loop (PV loop) catheters provide real-time ventricular pressure-volume loop data, enabling a complete assessment of cardiac function from a single catheterization.

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Clinical Applications of Pressure-Volume Loop (PV Loop) Analysis

Cardiac Resynchronization Therapy (CRT)

PV Loops are used for real-time clinical decision making for pacemaker optimization related to tailoring vector settings, AV delay, and/or lead placement to each patient.

Heart Failure with Preserved Ejection Fraction (HFpEF)

PV loops are considered the “gold standard” for HFpEF diagnosis by monitoring several diastolic hemodynamic variables including, but not limited to: End-diastolic Pressure-Volume Relationship (EDPVR), Tau, and dP/dt.

Mechanical Circulatory Support

By using PV loops as a feedback mechanism, one can optimize a patient’s hemodynamic state resulting from acute or long-term mechanical circulatory support. Quantitative measures of ventricular energetics, diastolic function, and intra-ventricular dyssynchrony provide a comprehensive assessment of hemodynamic function tailored specifically to that patient.

Structural Heart Interventions

PV loops can be used as a real-time feedback tool regarding the efficacy of any structural heart intervention. To date, most users have focused on improving the efficacy of valve deployment in TAVR/TAVI and TMVR interventions or valve improvement via mitral valve clipping or valvuloplasty procedures.

Summary of the main clinical applications of pressure-volume (PV) analysis
2019 Bastos et al
Summary of clinical applications for right ventricular pressure-volume (PV) analysis
2021 Brener et al