Preload

Defining Preload: The Foundation of PV Loops

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Preload is a fundamental concept in cardiovascular physiology, especially in the context of pressure-volume (PV) loops. It refers to the ventricular wall stress or stretch at the end of diastole, determined by the volume of blood returning to the heart. Understanding preload is essential for clinicians, physiologists, and researchers as it directly influences cardiac function … Read more

Introduction to Ventricular Volume-Pressure Loops

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The ventricular volume-pressure loop is a cornerstone of cardiovascular physiology, offering a graphical representation of the relationship between pressure and volume within the heart’s ventricles during a cardiac cycle. By visualizing how the heart’s left ventricle operates, this loop aids in understanding key concepts like preload, afterload, contractility, and compliance. This article provides a foundational … Read more