Pathophysiology of Mitral Regurgitation and Its Impact on Pressure-Volume Loops

Mitral regurgitation (MR) is a common valvular heart disease characterized by the backward flow of blood from the left ventricle into the left atrium during systole. This abnormal blood flow significantly alters the normal hemodynamics of the heart and has a profound effect on the pressure-volume (PV) loops used to evaluate cardiac function. Understanding the … Read more