Patrick Sullivan 1. Introduction The pressure volume loop in mitral stenosis provides a visual and quantitative understanding of how a narrowed mitral valve affects cardiac dynamics. When systemic afterload rises, the left ventricle faces a double burden: reduced preload due to mitral obstruction and increased pressure to overcome peripheral resistance. This dual challenge leads to diminished stroke … Read more
Pressure volume loop analysis in cardiology examines the basic ventricular pressure-volume relationships throughout the cardiac cycle to elucidate cardiac mechanics and energy utilization. This method offers an integrative view of both systolic and diastolic function, providing cardiologists with a powerful diagnostic and research tool. Introduction to Pressure Volume Loops Definition and Significance A pressure-volume (PV) … Read more
Introduction to Pressure Volume Catheters A pressure volume catheter is a sophisticated medical device used primarily in cardiac physiology to obtain real-time measurements of ventricular pressure and volume. These measurements are crucial in generating pressure-volume loops that help assess the heart’s mechanical performance. Initially developed for research, this technology has evolved into a critical clinical … Read more
Early Triumphs in the American Market CD Leycom’s journey began on a high note. After entering the United States, the company quickly gained traction, securing partnerships and demonstrating sustained growth. Fueled by a clear vision to revolutionize cardiac diagnostics, the team found early success translating their innovative concepts into tangible lab results. Yet, even as … Read more
Introduction to Cardiac Mechanics Understanding how the heart functions goes beyond just knowing that it pumps blood. At its core, cardiac mechanics provides a detailed explanation of how the heart generates pressure, moves volumes of blood, and responds to physiological demands. Among the many tools used to evaluate cardiac function, the PV loop and Frank … Read more
Introduction to Myocardial Work and Cardiac Reserve The heart is an incredible muscle—relentlessly beating to pump blood and meet the body’s demands. But what happens when those demands increase? Whether you’re exercising, climbing stairs, or under physiological stress, your heart must rise to the occasion. This capacity is known as cardiac reserve, and it’s closely … Read more
Introduction to Real-Time PV Loop Monitoring In the evolving landscape of cardiac surgery, patient safety and outcome optimization are paramount. One of the most innovative tools supporting these goals is real-time PV loop monitoring. This advanced technique provides clinicians with a dynamic view of the heart’s mechanical function, allowing them to assess how well it … Read more
The RV PV loop is a powerful graphical representation that describes the pressure-volume relationship of the right ventricle. As a fundamental model, it plays a key role in understanding right ventricular mechanics. Unlike its left-sided counterpart, the right ventricle exhibits unique structural, functional, and hemodynamic features, making this loop crucial for both clinical assessment and … Read more
Introduction The assessment of intraventricular dyssynchrony is crucial in diagnosing and managing heart failure and other cardiac dysfunctions. Among the various measurement techniques, conductance catheterization has emerged as a powerful tool for real-time, high-fidelity intracardiac volume assessment. This article explores the fundamental principles and methodologies behind conductance catheter measures of intraventricular dyssynchrony, setting the foundation … Read more
Introduction The Pmax derivation of contractility is a crucial concept in cardiovascular physiology, particularly in understanding the heart’s ability to generate force during systole. This principle is closely related to the End-Systolic Pressure-Volume Relationship (ESPVR), which serves as a key indicator of myocardial contractility. By analyzing Pmax, or the theoretical maximum pressure the ventricle can … Read more