Pmax derivation of contractility (ESPVR): Fundamentals and Basic Concepts

Introduction The Pmax derivation of contractility is a crucial concept in cardiovascular physiology, particularly in understanding the heart’s ability to generate force during systole. This principle is closely related to the End-Systolic Pressure-Volume Relationship (ESPVR), which serves as a key indicator of myocardial contractility. By analyzing Pmax, or the theoretical maximum pressure the ventricle can … Read more