EDPVR

Understanding the End-diastolic Pressure-Volume Relationship (EDPVR): A Complete Guide

by

Introduction to Cardiac Pressure-Volume Relationships The heart is often described as a pump, but this description doesn’t fully capture its complexity. To truly understand how the ventricles work, cardiologists rely on pressure-volume (PV) relationships. These curves provide a window into the interplay between pressure and volume during the cardiac cycle, revealing both systolic and diastolic … Read more

Computational Modeling of Beta Effects: End-Diastolic Pressure-Volume Relationship

by

Introduction Cardiac function is a complex interplay of mechanical and biochemical factors. One of the key parameters in assessing diastolic function is the end-diastolic pressure-volume relationship (EDPVR), which describes how ventricular pressure changes with volume at the end of diastole. This relationship is influenced by myocardial stiffness, loading conditions, and autonomic regulation, particularly the effect … Read more