Patrick Sullivan

Applications of Pressure Volume Loops in Research and Clinical Trials: Advancing Cardiovascular Medicine

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Introduction Pressure-volume (PV) loops have become an essential tool in cardiovascular research and clinical trials. These sophisticated graphical representations of the relationship between pressure and volume in the heart during a cardiac cycle offer deep insights into the mechanics of heart function. Researchers and clinicians have leveraged PV loops to advance the understanding of heart … Read more

Pressure-Volume Relationship in Blood Vessels: Insights into Arterial Stiffness and Its Impact on Hypertension and Cardiovascular Diseases

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The circulatory system is an intricate network where the heart and blood vessels work together to maintain the body’s blood flow. Central to this system is the pressure-volume relationship in blood vessels, a critical factor in determining vascular health and understanding various cardiovascular diseases. The elasticity, or stiffness, of arteries plays a significant role in … Read more

Pressure-Volume Loop Basics: An Overview of What PV Loops Represent and How They Relate to Cardiac Cycles

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Introduction The human heart is a marvel of biological engineering, tirelessly working to pump blood throughout the body. One of the most insightful ways to understand and evaluate cardiac function is through the use of Pressure-Volume (PV) loops. These loops offer a visual representation of the relationship between the pressure inside the heart’s chambers and … Read more