Introduction Pressure-volume (PV) loops are essential tools in cardiovascular physiology, offering valuable insights into cardiac function and hemodynamic status. In cardiogenic shock, where the heart struggles to pump blood effectively, PV loops provide a critical window into the mechanics of ventricular performance. A key phenomenon observed in this state is impaired preload responsiveness due to … Read more
Introduction Understanding preload reduction is critical in cardiovascular physiology, particularly when assessing cardiac function using the multi-beat PV loop measure. Preload refers to the ventricular end-diastolic volume, which directly influences stroke volume and overall cardiac output. Excessive preload can lead to complications such as heart failure, pulmonary congestion, and inefficient cardiac performance. The multi-beat PV … Read more
Introduction Cardiac function is a complex interplay of mechanical and biochemical factors. One of the key parameters in assessing diastolic function is the end-diastolic pressure-volume relationship (EDPVR), which describes how ventricular pressure changes with volume at the end of diastole. This relationship is influenced by myocardial stiffness, loading conditions, and autonomic regulation, particularly the effect … Read more
Introduction The RV PV Loop (Right Ventricular Pressure-Volume Loop) is a fundamental tool used to assess the dynamic function of the right ventricle (RV) under varying physiological and pathological conditions. One of the key disruptions in right ventricular function is pulmonary valve leakage, also known as pulmonary regurgitation. This condition results in the backward flow … Read more
Introduction The left atrial (LA) pressure-volume (PV) loop is a crucial tool for understanding the mechanical function of the left atrial chamber in the heart. With left atrial enlargement (LAE), significant changes occur in the compliance and function of the left atrial, affecting cardiovascular performance. This article explores how PV loops change due to left … Read more
Introduction The human cardiovascular system operates through a complex interplay between the heart and blood vessels to maintain optimal circulation. A critical aspect of this interaction is ventriculo-arterial coupling, which describes the balance between cardiac contractility and arterial load. This balance ensures efficient energy transfer from the heart to the arteries, optimizing cardiac output and … Read more
Introduction Congenitally Corrected Transposition of the Great Arteries (CCTGA) is a rare congenital heart defect characterized by atrioventricular and ventriculoarterial discordance. The right ventricle (RV) assumes systemic circulation, which can lead to progressive dysfunction over time. Surgical intervention may be required, but assessing preoperative risk remains a challenge. Pressure-volume (PV loops) analysis has emerged as … Read more
Introduction Advancements in cardiac monitoring technology have transformed how clinicians assess heart function in real-time, particularly in intraoperative and critical care settings. Two pivotal innovations—Baan’s Equation and PV Loop catheter technologies—offer a synergistic approach to improving hemodynamic evaluation. Baan’s Equation provides a mathematical model to estimate ventricular volume, while the PV Loop catheter enables real-time … Read more
Introduction The fundamentals of PV Loops and Potential Energy are essential for understanding cardiac mechanics and energy transfer within the heart. The PV loop (pressure-volume loop) graphically represents the changes in pressure and volume throughout the cardiac cycle, allowing researchers and clinicians to assess heart function dynamically. By analyzing the area enclosed within the PV … Read more
Introduction The heart is a highly efficient mechanical pump, continuously adjusting to changes in vascular conditions to maintain optimal cardiac output. A critical tool for analyzing cardiac function is the pressure-volume (PV) loop, which provides real-time insight into how the heart adapts to various physiological and pathological conditions. Among the many factors influencing cardiac performance, … Read more