Pathophysiology of Systolic Heart Failure through Pressure-Volume Loops

Understanding the pathophysiology of systolic heart failure is crucial to diagnosing and treating this condition effectively. One of the most insightful methods to examine heart function in systolic heart failure is by analyzing the pressure-volume loop. This graphical representation provides a comprehensive view of the changes in stroke volume, contractility, and overall left ventricular function … Read more

Mechanisms of Contractility in PV Loops: Understanding Myocardial Fiber Tension

Pressure-volume (PV) loops are a cornerstone in understanding cardiac physiology, offering a graphical representation of the relationship between pressure and volume within the heart during a cardiac cycle. These loops provide critical insights into ventricular function, particularly contractility, which is the intrinsic ability of the heart muscle (myocardium) to generate force during contraction, independent of … Read more

Comparison of Acute Responses: PV Loop-Guided vs Traditional CRT

Cardiac Resynchronization Therapy (CRT) has become a cornerstone in treating patients with heart failure (HF), specifically those who exhibit electrical dyssynchrony. It works by improving the synchrony of ventricular contractions, which enhances the overall efficiency of the heart. Traditionally, CRT has been guided by ECG and imaging techniques such as echocardiography to ensure optimal lead … Read more