Mitral regurgitation (MR) is a common valvular heart disease characterized by the backward flow of blood from the left ventricle into the left atrium during systole. This abnormal blood flow significantly alters the normal hemodynamics of the heart and has a profound effect on the pressure-volume (PV) loops used to evaluate cardiac function. Understanding the … Read more
Valvular heart disease (VHD) presents significant challenges in modern cardiovascular medicine. It encompasses a spectrum of conditions where one or more of the heart’s valves malfunction, leading to disrupted blood flow within the heart and across the systemic circulation. As VHD progresses, it often necessitates surgical intervention to correct the valve dysfunction. One of the … Read more
Introduction Aortic stenosis (AS) is a common and serious condition affecting the heart’s aortic valve, leading to restricted blood flow from the left ventricle to the aorta. This obstruction can cause significant cardiac dysfunction and is associated with a variety of symptoms, including chest pain, fainting, and shortness of breath. Accurate diagnosis and assessment of … Read more
The circulatory system is an intricate network where the heart and blood vessels work together to maintain the body’s blood flow. Central to this system is the pressure-volume relationship in blood vessels, a critical factor in determining vascular health and understanding various cardiovascular diseases. The elasticity, or stiffness, of arteries plays a significant role in … Read more
Introduction The human heart is a marvel of biological engineering, tirelessly working to pump blood throughout the body. One of the most insightful ways to understand and evaluate cardiac function is through the use of Pressure-Volume (PV) loops. These loops offer a visual representation of the relationship between the pressure inside the heart’s chambers and … Read more