CD Leycom provides medical devices for continuous, real-time measurement of cardiac function and performance
In addition to volume, intra-cardiac pressure is recorded simultaneously to produce continuous real-time images, known as Pressure-Volume (PV) loops — widely recognized as a “gold standard” of cardiac function and performance.
Pressure-volume (PV) loops provide insights on all aspects of heart function, which has proven to be invaluable for cardiac research and in guiding select cardiac interventions where comprehensive quantitative data is needed.
Pressure-Volume (PV) Loops
for Clinical Diagnoses and Life Science Research
Clinical Applications of Pressure-Volume Analysis
PV Loops are used for real-time clinical decision making for pacemaker optimization related to tailoring vector settings, AV delay, and/or lead placement to each patient.
PV loops are considered the “gold standard” for HFpEF diagnosis by monitoring several diastolic hemodynamic variables including, but not limited to: End-diastolic Pressure-Volume Relationship (EDPVR), Tau, and dP/dt.
By using PV loops as a feedback mechanism, one can optimize a patient’s hemodynamic state resulting from acute or long-term mechanical circulatory support. Quantitative measures of ventricular energetics, diastolic function, and intra-ventricular dyssynchrony provide a comprehensive assessment of hemodynamic function tailored specifically to that patient.
PV loops can be used as a real-time feedback tool regarding the efficacy of any structural heart intervention. To date, most users have focused on improving the efficacy of valve deployment in TAVR/TAVI and TMVR interventions or valve improvement via mitral valve clipping or valvuloplasty procedures.